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Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein Degradation.
Zhang, Jing; Fu, Liqiang; Shen, Bin; Liu, Yingtao; Wang, Wenqian; Cai, Xin; Kong, Linglong; Yan, Yilin; Meng, Ryan; Zhang, Zhuming; Chen, Ying-Nan P; Liu, Qian; Wan, Zhao-Kui; Zhou, Tianyuan; Wang, Xiaotao; Gavine, Paul; Del Rosario, Amanda; Ahn, Kay; Philippar, Ulrike; Attar, Ricardo; Yang, Jennifer; Xu, Yanping; Edwards, James P; Dai, Xuedong.
Affiliation
  • Zhang J; Oncology Biology, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Fu L; Medicinal Chemistry, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Shen B; Oncology Biology, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Liu Y; Medicinal Chemistry, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Wang W; Oncology Biology, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Cai X; Biomarker, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Kong L; Medicinal Chemistry, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Yan Y; Biomarker, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Meng R; Nonclinical Safety, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Zhang Z; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477, USA.
  • Chen YP; Oncology Biology, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Liu Q; Medicinal Chemistry, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Wan ZK; Medicinal Chemistry, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Zhou T; Oncology Biology, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Wang X; Biomarker, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Gavine P; Oncology Biology, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Del Rosario A; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477, USA.
  • Ahn K; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477, USA.
  • Philippar U; Janssen Research & Development, Turnhoutseweg 30, 2340 Beerse, Belgium.
  • Attar R; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477, USA.
  • Yang J; Oncology Biology, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Xu Y; Medicinal Chemistry, Janssen (China) Research & Development Center, Shanghai 201210, China.
  • Edwards JP; Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477, USA.
  • Dai X; Medicinal Chemistry, Janssen (China) Research & Development Center, Shanghai 201210, China. Electronic address: xdai18@its.jnj.com.
Cell Chem Biol ; 27(12): 1500-1509.e13, 2020 12 17.
Article in En | MEDLINE | ID: mdl-32888499
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Protein Kinase Inhibitors / Interleukin-1 Receptor-Associated Kinases / Proteolysis Limits: Humans Language: En Journal: Cell Chem Biol Year: 2020 Document type: Article Affiliation country: China Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Large B-Cell, Diffuse / Protein Kinase Inhibitors / Interleukin-1 Receptor-Associated Kinases / Proteolysis Limits: Humans Language: En Journal: Cell Chem Biol Year: 2020 Document type: Article Affiliation country: China Country of publication: United States