Differential response to cytotoxic therapy explains treatment dynamics of acute myeloid leukaemia patients: insights from a mathematical modelling approach.

Hoffmann, H; Thiede, C; Glauche, I; Bornhaeuser, M; Roeder, I

Hoffmann, H; Thiede, C; Glauche, I; Bornhaeuser, M; Roeder, I.

Affiliation

Hoffmann H; Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, TU Dresden, Dresden, Germany.
Thiede C; Medical Clinic and Polyclinic I, University Hospital Dresden Carl Gustav Carus, TU Dresden, Dresden, Germany.
Glauche I; Institute for Medical Informatics and Biometry, Carl Gustav Carus Faculty of Medicine, TU Dresden, Dresden, Germany.
Bornhaeuser M; Medical Clinic and Polyclinic I, University Hospital Dresden Carl Gustav Carus, TU Dresden, Dresden, Germany.
Roeder I; National Center for Tumor Diseases (NCT), Partner Site Dresden, Dresden, Germany.

J R Soc Interface ; 17(170): 20200091, 2020 09.

Article in En | MEDLINE | ID: mdl-32900301

Subject(s)

Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Humans; Leukemia, Myeloid, Acute/drug therapy; Models, Theoretical; Remission Induction; Risk Assessment

Key words

acute myeloid leukaemia; leukaemia; mathematical modelling; measurable residual disease; relapse prediction; risk stratification

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Neoplasm Recurrence, Local Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J R Soc Interface Year: 2020 Document type: Article Affiliation country: Germany Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google