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Restoring the natural tropism of AAV2 vectors for human liver.
Cabanes-Creus, Marti; Hallwirth, Claus V; Westhaus, Adrian; Ng, Boaz H; Liao, Sophia H Y; Zhu, Erhua; Navarro, Renina Gale; Baltazar, Grober; Drouyer, Matthieu; Scott, Suzanne; Logan, Grant J; Santilli, Giorgia; Bennett, Antonette; Ginn, Samantha L; McCaughan, Geoff; Thrasher, Adrian J; Agbandje-McKenna, Mavis; Alexander, Ian E; Lisowski, Leszek.
Affiliation
  • Cabanes-Creus M; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.
  • Hallwirth CV; Gene Therapy Research Unit, Children's Medical Research Institute and Children's Hospital at Westmead, Faculty of Medicine and Health, The University of Sydney and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia.
  • Westhaus A; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.
  • Ng BH; Great Ormond Institute of Child Health, University College London, WC1N 1EH London, UK.
  • Liao SHY; Vector and Genome Engineering Facility, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.
  • Zhu E; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.
  • Navarro RG; Gene Therapy Research Unit, Children's Medical Research Institute and Children's Hospital at Westmead, Faculty of Medicine and Health, The University of Sydney and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia.
  • Baltazar G; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.
  • Drouyer M; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.
  • Scott S; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, NSW 2145, Australia.
  • Logan GJ; Gene Therapy Research Unit, Children's Medical Research Institute and Children's Hospital at Westmead, Faculty of Medicine and Health, The University of Sydney and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia.
  • Santilli G; Commonwealth Scientific and Industrial Research Organisation (CSIRO), North Ryde, NSW 2113, Australia.
  • Bennett A; Gene Therapy Research Unit, Children's Medical Research Institute and Children's Hospital at Westmead, Faculty of Medicine and Health, The University of Sydney and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia.
  • Ginn SL; Great Ormond Institute of Child Health, University College London, WC1N 1EH London, UK.
  • McCaughan G; Department of Biochemistry and Molecular Biology, Center for Structural Biology, University of Florida, Gainesville, FL 32610, USA.
  • Thrasher AJ; Gene Therapy Research Unit, Children's Medical Research Institute and Children's Hospital at Westmead, Faculty of Medicine and Health, The University of Sydney and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia.
  • Agbandje-McKenna M; Liver Injury and Cancer Program, Centenary Research Institute, A.W Morrow Gastroenterology and Liver Centre, Australian National Liver Transplant Unit, Royal Prince Alfred Hospital, The University of Sydney, Sydney, NSW 2006, Australia.
  • Alexander IE; Great Ormond Institute of Child Health, University College London, WC1N 1EH London, UK.
  • Lisowski L; Department of Biochemistry and Molecular Biology, Center for Structural Biology, University of Florida, Gainesville, FL 32610, USA.
Sci Transl Med ; 12(560)2020 09 09.
Article in En | MEDLINE | ID: mdl-32908003

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dependovirus / Genetic Vectors Limits: Animals / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2020 Document type: Article Affiliation country: Australia Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dependovirus / Genetic Vectors Limits: Animals / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2020 Document type: Article Affiliation country: Australia Country of publication: United States