Potassium losing, aldosterone producing adrenocortical carcinoma: a rare presentation.
BMJ Case Rep
; 13(9)2020 Sep 09.
Article
in En
| MEDLINE
| ID: mdl-32912887
ABSTRACT
Adrenocortical carcinomas (ACCs) are rare malignancies with an incidence of one to two per million per year. Aldosterone-producing ACCs (APACs) are extremely rare with an incidence less than 1%. We describe a rare case of APAC, presenting with episodic lower-limb weakness and hypertension. Our patient was found to have serum aldosterone levels of 20.8 ng/dL (2.5-15.2) with persistent hypokalaemia and a 9.7×8.3×7.7 cm right adrenal mass, which was suspicious of malignancy on evaluation. He underwent a complete surgical resection which confirmed the diagnosis of ACC and normalised his aldosterone and potassium levels. He was then subjected to postoperative chemotherapy. Postoperative adjuvant chemotherapy with mitotane has a role in preventing recurrence.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Adrenal Cortex Neoplasms
/
Adrenocortical Carcinoma
/
Adrenalectomy
/
Hypokalemic Periodic Paralysis
/
Aldosterone
/
Hypertension
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
BMJ Case Rep
Year:
2020
Document type:
Article
Affiliation country:
India