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Rac1 conditional deletion attenuates retinal ganglion cell apoptosis by accelerating autophagic flux in a mouse model of chronic ocular hypertension.
Zhang, Meng-Lu; Zhao, Guo-Li; Hou, Yu; Zhong, Shu-Min; Xu, Lin-Jie; Li, Fang; Niu, Wei-Ran; Yuan, Fei; Yang, Xiong-Li; Wang, Zhongfeng; Miao, Yanying.
Affiliation
  • Zhang ML; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
  • Zhao GL; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
  • Hou Y; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
  • Zhong SM; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
  • Xu LJ; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
  • Li F; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
  • Niu WR; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
  • Yuan F; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
  • Yang XL; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
  • Wang Z; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China. zfwang@fudan.edu.cn.
  • Miao Y; Department of Ophthalmology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, 200032, Shanghai, China. yymiao@fudan.edu.cn.
Cell Death Dis ; 11(9): 734, 2020 09 10.
Article in En | MEDLINE | ID: mdl-32913260
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Retinal Ganglion Cells / Ocular Hypertension / Rac1 GTP-Binding Protein Limits: Animals / Humans / Male Language: En Journal: Cell Death Dis Year: 2020 Document type: Article Affiliation country: China Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Retinal Ganglion Cells / Ocular Hypertension / Rac1 GTP-Binding Protein Limits: Animals / Humans / Male Language: En Journal: Cell Death Dis Year: 2020 Document type: Article Affiliation country: China Country of publication: United kingdom