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Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity.
McKeithan, Wesley L; Feyen, Dries A M; Bruyneel, Arne A N; Okolotowicz, Karl J; Ryan, Daniel A; Sampson, Kevin J; Potet, Franck; Savchenko, Alex; Gómez-Galeno, Jorge; Vu, Michelle; Serrano, Ricardo; George, Alfred L; Kass, Robert S; Cashman, John R; Mercola, Mark.
Affiliation
  • McKeithan WL; Cardiovascular Institute and Department of Medicine, Stanford University, Stanford, CA 94305, USA; Graduate School of Biomedical Sciences, Sanford Burnham Prebys Medical Discovery Institute, San Diego, CA 92037, USA.
  • Feyen DAM; Cardiovascular Institute and Department of Medicine, Stanford University, Stanford, CA 94305, USA.
  • Bruyneel AAN; Cardiovascular Institute and Department of Medicine, Stanford University, Stanford, CA 94305, USA.
  • Okolotowicz KJ; Human BioMolecular Research Institute, San Diego, CA 92121, USA.
  • Ryan DA; Human BioMolecular Research Institute, San Diego, CA 92121, USA.
  • Sampson KJ; Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
  • Potet F; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Savchenko A; Cardiovascular Institute and Department of Medicine, Stanford University, Stanford, CA 94305, USA.
  • Gómez-Galeno J; Human BioMolecular Research Institute, San Diego, CA 92121, USA.
  • Vu M; Cardiovascular Institute and Department of Medicine, Stanford University, Stanford, CA 94305, USA.
  • Serrano R; Cardiovascular Institute and Department of Medicine, Stanford University, Stanford, CA 94305, USA.
  • George AL; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Kass RS; Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
  • Cashman JR; Human BioMolecular Research Institute, San Diego, CA 92121, USA.
  • Mercola M; Cardiovascular Institute and Department of Medicine, Stanford University, Stanford, CA 94305, USA; Graduate School of Biomedical Sciences, Sanford Burnham Prebys Medical Discovery Institute, San Diego, CA 92037, USA. Electronic address: mmercola@stanford.edu.
Cell Stem Cell ; 27(5): 813-821.e6, 2020 11 05.
Article in En | MEDLINE | ID: mdl-32931730
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells Limits: Humans Language: En Journal: Cell Stem Cell Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells Limits: Humans Language: En Journal: Cell Stem Cell Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States