[Vaccination against Haemophilus influenzaetype b; why and how?] / Vaccinatie tegenHaemophilus influenzaetype b.
Ned Tijdschr Geneeskd
; 1642020 09 03.
Article
in Nl
| MEDLINE
| ID: mdl-32940992
ABSTRACT
After a development period of around 13 years, in 1993 the vaccination against infections caused by Haemophilus influenzae type b (Hib) was introduced into the Dutch National Immunisation Programme. Before the introduction of the vaccination, the burden of disease was high; every year around 700 children acquired an invasive Hib infection, half of whom developed meningitis. Of those children with Hib-related meningitis, 2% died and more than 8% were left with severe residual symptoms. Furthermore, at least one-third of those who recovered developed learning and concentration problems. Hib also caused other infections such as epiglottitis, osteomyelitis and arthritis. Initially, the conjugated Hib vaccine PRP-T was given as a separate injection. From 2005 onwards PRP-T was included in the combination DTaP-IPV-Hib vaccine, and since 2011 PRP-T has been part of the DTaP-IPV-Hib-HepB vaccine. Although H. influenzae is still around, invasive Hib infections in children now occur only very rarely.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tetanus Toxoid
/
Haemophilus Vaccines
/
Haemophilus influenzae type b
/
Haemophilus Infections
Limits:
Child, preschool
/
Humans
/
Infant
Language:
Nl
Journal:
Ned Tijdschr Geneeskd
Year:
2020
Document type:
Article