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Clinical Characteristics, Management, and Factors Associated with Poor Visual Prognosis of Acute Retinal Necrosis.
Takase, Hiroshi; Goto, Hiroshi; Namba, Kenichi; Mizuki, Nobuhisa; Okada, Annabelle A; Ohguro, Nobuyuki; Sonoda, Koh-Hei; Tomita, Makoto; Keino, Hiroshi; Kezuka, Takeshi; Kubono, Reo; Mizuuchi, Kazuomi; Shibuya, Etsuko; Takahashi, Hiroyuki; Yanai, Ryoji; Mochizuki, Manabu.
Affiliation
  • Takase H; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Goto H; Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.
  • Namba K; Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Mizuki N; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Kanagawa, Japan.
  • Okada AA; Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan.
  • Ohguro N; Department of Ophthalmology, Japan Community Health Care Organization Osaka Hospital, Osaka, Japan.
  • Sonoda KH; Department of Ophthalmology, Kyushu University Graduate School of Medicine, Fukuoka, Japan.
  • Tomita M; School of Data Science, Yokohama City University, Kanagawa, Japan.
  • Keino H; Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan.
  • Kezuka T; Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.
  • Kubono R; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Mizuuchi K; Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Shibuya E; Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Kanagawa, Japan.
  • Takahashi H; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
  • Yanai R; Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.
  • Mochizuki M; Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Ocul Immunol Inflamm ; 30(1): 48-53, 2022 Jan 02.
Article in En | MEDLINE | ID: mdl-32945715
ABSTRACT

Purpose:

To identify the clinical characteristics of acute retinal necrosis (ARN) and clarify factors associated with poor visual prognosis.

Methods:

a nationwide multi-center retrospective chart review study was performed in Japan using data from the medical records of 149 consecutive ARN patients. Demographics, ocular signs, virologic testing of intraocular fluids, and treatment were examined. Factors associated with poor visual prognosis were investigated by regression analysis.

Results:

At initial presentation, anterior chamber cells or mutton-fat keratic precipitates (97%), unilaterality (93%), and yellow-white retinal lesions (86%) were recognized. In the clinical course, rapid circumferential expansion of retinal lesions (39%), development of retinal break or retinal detachment (55%), and optic atrophy (43%) were recorded. Four variables were identified as associated with poor visual prognosis.

Conclusions:

The present study identified clinical characteristics and factors associated with poor visual prognosis of ARN.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Detachment / Retinal Necrosis Syndrome, Acute Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Ocul Immunol Inflamm Journal subject: ALERGIA E IMUNOLOGIA / OFTALMOLOGIA Year: 2022 Document type: Article Affiliation country: Japan Publication country: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Detachment / Retinal Necrosis Syndrome, Acute Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Ocul Immunol Inflamm Journal subject: ALERGIA E IMUNOLOGIA / OFTALMOLOGIA Year: 2022 Document type: Article Affiliation country: Japan Publication country: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM