Ultraviolet photodissociation of fondaparinux generates signature antithrombin-like 3-O-sulfated -GlcNS3S6S- monosaccharide fragment (Y<sub>3</sub>/C<sub>3</sub>).

Hawkridge, Adam M; Hackbusch, Sven

Ultraviolet photodissociation of fondaparinux generates signature antithrombin-like 3-O-sulfated -GlcNS3S6S- monosaccharide fragment (Y₃/C₃).

Hawkridge, Adam M; Hackbusch, Sven.

Affiliation

Hawkridge AM; Department of Pharmaceutics and Pharmacotherapy & Outcomes Science, Virginia Commonwealth University School of Pharmacy, Richmond, VA, 23298, USA. amhawkridge@vcu.edu.
Hackbusch S; Institute for Structural Biology, Drug Discovery, and Development, Virginia Commonwealth University, Richmond, VA, 23298, USA. amhawkridge@vcu.edu.

Anal Bioanal Chem ; 412(28): 7925-7935, 2020 Nov.

Article in En | MEDLINE | ID: mdl-32945907

Subject(s)

Antithrombins/chemistry; Fondaparinux/radiation effects; Glycosaminoglycans/chemistry; Monosaccharides/chemistry; Ultraviolet Rays; Chromatography, Liquid/methods; Fondaparinux/chemistry; Tandem Mass Spectrometry/methods

Key words

3-O Sulfation; Glycosaminoglycans; Heparin; Mass spectrometry; UVPD

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ultraviolet Rays / Antithrombins / Fondaparinux / Glycosaminoglycans / Monosaccharides Language: En Journal: Anal Bioanal Chem Year: 2020 Document type: Article Affiliation country: United States Country of publication: Germany

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google