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Safety, immunogenicity, and efficacy of a Clostridioides difficile toxoid vaccine candidate: a phase 3 multicentre, observer-blind, randomised, controlled trial.
de Bruyn, Guy; Gordon, David L; Steiner, Theodore; Tambyah, Paul; Cosgrove, Catherine; Martens, Mark; Bassily, Ehab; Chan, Eng-Soon; Patel, Dhaval; Chen, Josh; Torre-Cisneros, Julian; Fernando De Magalhães Francesconi, Carlos; Gesser, Richard; Jeanfreau, Robert; Launay, Odile; Laot, Thelma; Morfin-Otero, Rayo; Oviedo-Orta, Ernesto; Park, Yoon Soo; Piazza, Franco M; Rehm, Christine; Rivas, Enrique; Self, Steve; Gurunathan, Sanjay.
Affiliation
  • de Bruyn G; Sanofi Pasteur, Swiftwater, PA, USA. Electronic address: guy.debruyn@sanofi.com.
  • Gordon DL; Department of Infectious Diseases and Microbiology, SA Pathology, Flinders Medical Centre, Bedford Park, SA, Australia.
  • Steiner T; Vancouver General Hospital, Vancouver, BC, Canada.
  • Tambyah P; National University of Singapore and National University Health System, Singapore.
  • Cosgrove C; Vaccine Institute, St George's University, London, UK.
  • Martens M; Reading Hospital, West Reading, PA, USA.
  • Bassily E; Sanofi Pasteur, Swiftwater, PA, USA.
  • Chan ES; Sanofi Pasteur, Toronto, ON, Canada.
  • Patel D; Sanofi Pasteur, Swiftwater, PA, USA.
  • Chen J; Sanofi Pasteur, Swiftwater, PA, USA.
  • Torre-Cisneros J; Hospital Universitario Reina Sofia-IMIBIC, University of Cordoba, Spanish Network for Research in Infectious Disease, Cordoba, Spain.
  • Fernando De Magalhães Francesconi C; Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
  • Gesser R; Sanofi Pasteur, Swiftwater, PA, USA.
  • Jeanfreau R; MedPharmics, Metairie, LA, USA.
  • Launay O; Université Paris Descartes, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France.
  • Laot T; Sanofi Pasteur, Manila, Philippines.
  • Morfin-Otero R; Antiguo Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Mexico.
  • Oviedo-Orta E; Sanofi Pasteur, Lyon, France; Celgene Corporation, Summit, NJ, USA.
  • Park YS; Department of Internal Medicine, National Health Insurance Service, Ilsan Hospital, Goyang, Korea.
  • Piazza FM; Sanofi Pasteur, Swiftwater, PA, USA.
  • Rehm C; Sanofi Pasteur, Swiftwater, PA, USA.
  • Rivas E; Sanofi Pasteur, Mexico City, Mexico.
  • Self S; Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Gurunathan S; Sanofi Pasteur, Swiftwater, PA, USA.
Lancet Infect Dis ; 21(2): 252-262, 2021 02.
Article in En | MEDLINE | ID: mdl-32946836
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Vaccines / Clostridioides difficile / Clostridium Infections Type of study: Clinical_trials Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Lancet Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2021 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Vaccines / Clostridioides difficile / Clostridium Infections Type of study: Clinical_trials Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Lancet Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2021 Document type: Article Country of publication: United States