A double burden of tuberculosis and diabetes mellitus and the possible role of vitamin D deficiency.
Clin Nutr
; 40(2): 350-357, 2021 02.
Article
in En
| MEDLINE
| ID: mdl-32948348
ABSTRACT
Tuberculosis remains a major global health challenge, particularly in low-to-middle income countries such as China. At the same time, the country is facing a rapidly increasing diabetes incidence over the last 10 years. Diabetes aggravates the tuberculosis epidemic which poses a serious challenge in public health. In recent years, the high prevalence of vitamin D deficiency represents a global health problem, which is also associated with the risk of diabetes, and tuberculosis. Therefore, this review aims to provide an overall and updated understanding of the epidemiology of co-occurrence of tuberculosis and diabetes in China, and to elucidate the possible role of vitamin D deficiency. In conclusion, significant aggravation of the tuberculosis epidemic due to diabetes may exist in China for a relatively long period of time to come. Further, the double burden and its implications to public health in this country may be significantly influenced by the high prevalence of vitamin D deficiency. Bidirectional screening for tuberculosis and diabetes is recommended, and extra vitamin D may benefit especially in a situation of a heavy tuberculosis burden combined with prevalent vitamin D deficiency. Longitudinal studies to verify the role of vitamin D deficiency in the double burden, and trials on the effect of vitamin D supplementation are needed in the future.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tuberculosis
/
Vitamin D
/
Vitamin D Deficiency
/
Diabetes Mellitus
/
Mycobacterium tuberculosis
Type of study:
Observational_studies
/
Prevalence_studies
Limits:
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Clin Nutr
Year:
2021
Document type:
Article