Optimization of Extraction of Bioactive Peptides from Monkfish (Lophius litulon) and Characterization of Their Role in H2O2-Induced Lesion.

Tian, Xiaoxiao; Zheng, Jiawen; Xu, Baogui; Ye, Jiena; Yang, Zuisu; Yuan, Falei

Optimization of Extraction of Bioactive Peptides from Monkfish (Lophius litulon) and Characterization of Their Role in H₂O₂-Induced Lesion.

Tian, Xiaoxiao; Zheng, Jiawen; Xu, Baogui; Ye, Jiena; Yang, Zuisu; Yuan, Falei.

Affiliation

Tian X; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Zheng J; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Xu B; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Ye J; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Yang Z; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Yuan F; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.

Mar Drugs ; 18(9)2020 Sep 17.

Article in En | MEDLINE | ID: mdl-32957435

Subject(s)

Antioxidants/pharmacology; Fish Proteins/pharmacology; Hydrogen Peroxide/toxicity; Macrophages/drug effects; Muscle Proteins/pharmacology; Oxidative Stress/drug effects; Reactive Oxygen Species/metabolism; Animals; Antioxidants/isolation & purification; Antioxidants/metabolism; Catalase/metabolism; Fish Proteins/isolation & purification; Fish Proteins/metabolism; Glutathione Peroxidase/metabolism; Macrophages/metabolism; Macrophages/pathology; Malondialdehyde/metabolism; Mice; Muscle Proteins/isolation & purification; Muscle Proteins/metabolism; Peptide Hydrolases/metabolism; Proteolysis; RAW 264.7 Cells; Superoxide Dismutase/metabolism

Key words

< 1 kDa peptides; antioxidant activity; monkfish (Lophius litulon); response surface methodology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reactive Oxygen Species / Oxidative Stress / Fish Proteins / Hydrogen Peroxide / Macrophages / Muscle Proteins / Antioxidants Limits: Animals Language: En Journal: Mar Drugs Journal subject: BIOLOGIA / FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: China Country of publication: Switzerland

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