Can MRI features differentiate ovarian mucinous carcinoma from mucinous borderline tumor?
Eur J Radiol
; 132: 109281, 2020 Nov.
Article
in En
| MEDLINE
| ID: mdl-32961452
ABSTRACT
PURPOSE:
Our purpose was to determine if MRI could be used to distinguish ovarian mucinous carcinoma (MC) from mucinous borderline tumor (MBT). MATERIALS ANDMETHODS:
This study included 63 consecutive patients with histopathologically proven ovarian mucinous neoplasms (11 MCs and 52 MBTs) who underwent preoperative contrast-enhanced MRI. MRI images were retrospectively reviewed and compared between the 2 pathologies.RESULTS:
The maximum tumor diameters (219.7⯱â¯80.8â¯mm vs. 177.4⯱â¯56.5â¯mm, pâ¯<⯠0.05) and maximum mural nodule (MN) diameters (41.7 ± 33.8 mm vs. 6.6 ± 8.9 mm, pâ¯<⯠0.01) were significantly larger in MCs than in MBTs. MNs larger than 5 mm (82 % vs. 29 %, pâ¯<⯠0.01) and abnormal ascites (45 % vs. 12 %, pâ¯<⯠0.05) were significantly more frequent in MCs than in MBTs. Apparent diffusion coefficient (ADC) values of MN were significantly lower in MCs than in MBTs (1.20 ± 0.25 × 10-3 mm2/s vs. 1.61⯱â¯0.35â¯×â¯10-3 mm2/s, pâ¯<⯠0.05). No significant difference was found in number of loculi, honeycomb sign, stained glass appearance, fluid-fluid level, thickened septa larger than 5 mm, peritoneal dissemination, or T2 hypointense microcysts between MCs and MBTs. T2 hypointense microcysts were observed only in 7 MBTs (13%).CONCLUSION:
MRI findings of these 2 pathologies overlapped considerably. Compared with MBTs, MCs exhibited larger tumor size, larger MN size, and lower ADC values of MN, and MCs more frequently had MNs larger than 5â¯mm and abnormal ascites. T2 hypointense microcysts might be a specific MRI finding in MBTs.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ovarian Neoplasms
/
Adenocarcinoma, Mucinous
Type of study:
Observational_studies
Limits:
Female
/
Humans
Language:
En
Journal:
Eur J Radiol
Year:
2020
Document type:
Article
Affiliation country:
Japan