Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin.

Nevídalová, Hana; Michalcová, Lenka; Glatz, Zdenek

Nevídalová, Hana; Michalcová, Lenka; Glatz, Zdenek.

Affiliation

Nevídalová H; Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic.
Michalcová L; Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic.
Glatz Z; Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic.

J Sep Sci ; 43(22): 4225-4233, 2020 Nov.

Article in En | MEDLINE | ID: mdl-32966669

Subject(s)

Chlorpropamide/analysis; Diclofenac/analysis; Flurbiprofen/analysis; Ibuprofen/analysis; Phenylbutazone/analysis; Tolbutamide/analysis; Binding Sites/drug effects; Chlorpropamide/pharmacology; Diclofenac/pharmacology; Electrophoresis, Capillary; Flurbiprofen/pharmacology; Humans; Ibuprofen/pharmacology; Lidocaine/antagonists & inhibitors; Lidocaine/chemistry; Phenylbutazone/pharmacology; Serum Albumin, Human/chemistry; Tolbutamide/pharmacology; Tryptophan/antagonists & inhibitors; Tryptophan/chemistry

Key words

binding constant; binding sites; capillary electrophoresis-frontal analysis; drug competition; human serum albumin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tolbutamide / Phenylbutazone / Chlorpropamide / Diclofenac / Flurbiprofen / Ibuprofen Limits: Humans Language: En Journal: J Sep Sci Year: 2020 Document type: Article Affiliation country: Czech Republic Country of publication: Germany

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