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Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.
Lawson, Keith A; Sousa, Cristovão M; Zhang, Xiaoyu; Kim, Eiru; Akthar, Rummy; Caumanns, Joseph J; Yao, Yuxi; Mikolajewicz, Nicholas; Ross, Catherine; Brown, Kevin R; Zid, Abdelrahman Abou; Fan, Zi Peng; Hui, Shirley; Krall, Jordan A; Simons, Donald M; Slater, Chloe J; De Jesus, Victor; Tang, Lujia; Singh, Richa; Goldford, Joshua E; Martin, Sarah; Huang, Qian; Francis, Elizabeth A; Habsid, Andrea; Climie, Ryan; Tieu, David; Wei, Jiarun; Li, Ren; Tong, Amy Hin Yan; Aregger, Michael; Chan, Katherine S; Han, Hong; Wang, Xiaowei; Mero, Patricia; Brumell, John H; Finelli, Antonio; Ailles, Laurie; Bader, Gary; Smolen, Gromoslaw A; Kingsbury, Gillian A; Hart, Traver; Kung, Charles; Moffat, Jason.
Affiliation
  • Lawson KA; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Sousa CM; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
  • Zhang X; Division of Urology, Department of Surgery, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Kim E; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Akthar R; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Caumanns JJ; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
  • Yao Y; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Mikolajewicz N; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ross C; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Brown KR; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
  • Zid AA; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Fan ZP; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Hui S; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
  • Krall JA; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Simons DM; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Slater CJ; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • De Jesus V; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Tang L; Institute for Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.
  • Singh R; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Goldford JE; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Martin S; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Huang Q; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Francis EA; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Habsid A; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Climie R; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Tieu D; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Wei J; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Li R; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Tong AHY; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Aregger M; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Chan KS; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Han H; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Wang X; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Mero P; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Brumell JH; Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Finelli A; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Ailles L; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Bader G; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Smolen GA; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Kingsbury GA; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Hart T; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
  • Kung C; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
  • Moffat J; Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Nature ; 586(7827): 120-126, 2020 10.
Article in En | MEDLINE | ID: mdl-32968282
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / Genome / Tumor Escape / Genomics / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2020 Document type: Article Affiliation country: Canada Country of publication: United kingdom
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / Genome / Tumor Escape / Genomics / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nature Year: 2020 Document type: Article Affiliation country: Canada Country of publication: United kingdom