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Identification of novel human USP2 inhibitor and its putative role in treatment of COVID-19 by inhibiting SARS-CoV-2 papain-like (PLpro) protease.
Mirza, Muhammad Usman; Ahmad, Sarfraz; Abdullah, Iskandar; Froeyen, Matheus.
Affiliation
  • Mirza MU; Department of Pharmaceutical and Pharmacological Sciences, Rega Institute for Medical Research, Medicinal Chemistry, University of Leuven, B-3000, Leuven, Belgium.
  • Ahmad S; Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, 50603, Malaysia.
  • Abdullah I; Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, 50603, Malaysia.
  • Froeyen M; Department of Pharmaceutical and Pharmacological Sciences, Rega Institute for Medical Research, Medicinal Chemistry, University of Leuven, B-3000, Leuven, Belgium. Electronic address: mathy.froeyen@kuleuven.be.
Comput Biol Chem ; 89: 107376, 2020 Dec.
Article in En | MEDLINE | ID: mdl-32979815
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Ubiquitin Thiolesterase / Coronavirus Protease Inhibitors / Coronavirus 3C Proteases / SARS-CoV-2 / COVID-19 Drug Treatment Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Comput Biol Chem Journal subject: BIOLOGIA / INFORMATICA MEDICA / QUIMICA Year: 2020 Document type: Article Affiliation country: Belgium Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Ubiquitin Thiolesterase / Coronavirus Protease Inhibitors / Coronavirus 3C Proteases / SARS-CoV-2 / COVID-19 Drug Treatment Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Comput Biol Chem Journal subject: BIOLOGIA / INFORMATICA MEDICA / QUIMICA Year: 2020 Document type: Article Affiliation country: Belgium Country of publication: United kingdom