HLA-G: Function, polymorphisms and pathology.
Int J Immunogenet
; 48(2): 172-192, 2021 Apr.
Article
in En
| MEDLINE
| ID: mdl-33001562
ABSTRACT
HLA-G immune modulatory genes and molecules are presently being studied by a widespread number of research groups. In the present study, we do not aim to be exhaustive since the number of manuscripts published every year is overwhelming. Instead, our aim is pointing out facts about HLA-G function, polymorphism and pathology that have been confirmed by several different researchers, together with exposing aspects that may have been overlooked or not sufficiently remarked in this productive field of study. On the other hand, we question whether performing mainly studies on HLA-G and disease associations is going to give a clear answer in the future, since 40 years of study of classical HLA molecules association with disease has still given no definite answer on this issue.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
HLA-G Antigens
Limits:
Animals
/
Female
/
Humans
/
Male
/
Pregnancy
Language:
En
Journal:
Int J Immunogenet
Journal subject:
ALERGIA E IMUNOLOGIA
/
GENETICA
Year:
2021
Document type:
Article
Affiliation country:
Spain