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A Designer Quest for the Achilles' Heel of Influenza.
Fajardo, J Eduardo; Fiser, Andras.
Affiliation
  • Fajardo JE; Department of Systems and Computational Biology, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY 10461, USA; Department of Biochemistry, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY 10461, USA.
  • Fiser A; Department of Systems and Computational Biology, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY 10461, USA; Department of Biochemistry, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY 10461, USA. Electronic address: andras.fiser@einsteinmed.org.
Structure ; 28(10): 1083-1084, 2020 10 06.
Article in En | MEDLINE | ID: mdl-33027689
Monoclonal antibodies are attractive but, in certain applications, limited therapeutic modalities due to their large size and high specificity. In this issue of Structure, Sevy at al. describe a computationally designed cyclic peptide mimicking the CDRH3 loop of the C05 antibody against influenza showing the potential utility of designer biologics.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza, Human Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Structure Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza, Human Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Structure Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States