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An innovative approach for determining the customized refractive index of ectatic corneas in cataractous patients.
Pirhadi, Shiva; Maghooli, Keivan; Jadidi, Khosrow.
Affiliation
  • Pirhadi S; Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.
  • Maghooli K; Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran. k_maghooli@srbiau.ac.ir.
  • Jadidi K; Vision Health Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Sci Rep ; 10(1): 16681, 2020 10 07.
Article in En | MEDLINE | ID: mdl-33028843
The aim of this study is to determine the customized refractive index of ectatic corneas and also propose a method for determining the corneal and IOL power in these eyes. Seven eyes with moderate and severe corneal ectatic disorders, which had been under cataract surgery, were included. At least three months after cataract surgery, axial length, cornea, IOL thickness and the distance between IOL from cornea, and aberrometry were measured. All the measured points of the posterior and anterior parts of the cornea converted to points cloud and surface by using the MATLAB and Solidworks software. The implanted IOLs were designed by Zemax software. The ray tracing analysis was performed on the customized eye models, and the corneal refractive index was determined by minimizing the difference between the measured aberrations from the device and resulted aberrations from the simulation. Then, by the use of preoperative corneal images, corneal power was calculated by considering the anterior and posterior parts of the cornea and refractive index of 1.376 and the customized corneal refractive index in different regions and finally it was entered into the IOL power calculation formulas. The corneal power in the 4 mm region and the Barrett formula resulted the prediction error of six eyes within ± 1 diopter. It seems that using the total corneal power along with the Barrett formula can prevent postoperative hyperopic shift, especially in eyes with advanced ectatic disorders.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Refraction, Ocular / Cornea / Corneal Diseases Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: Iran Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Refraction, Ocular / Cornea / Corneal Diseases Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: Iran Country of publication: United kingdom