Antigenic competition in the generation of multi-virus-specific cell lines for immunotherapy of human cytomegalovirus, polyomavirus BK, Epstein-Barr virus and adenovirus infection in haematopoietic stem cell transplant recipients.

Roubalová, Katerina; Nemecková, Sárka; Krystofová, Jitka; Hainz, Petr; Pumannová, Markéta; Hamsíková, Eva

Roubalová, Katerina; Nemecková, Sárka; Krystofová, Jitka; Hainz, Petr; Pumannová, Markéta; Hamsíková, Eva.

Affiliation

Roubalová K; Department of Immunology, Institute of Hematology and Blood Transfusion, Prague, Czech Republic. Electronic address: roubalova@uhkt.cz.
Nemecková S; Department of Immunology, Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
Krystofová J; Department of Immunology, Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
Hainz P; Department of Immunology, Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
Pumannová M; National Reference Laboratory for Herpesviruses, National Institute of Public Health, Prague, Czech Republic.
Hamsíková E; National Reference Laboratory for Papillomaviruses and Polyomaviruses, Institute of Hematology and Blood Transfusion, Prague, Czech Republic.

Immunol Lett ; 228: 64-69, 2020 12.

Article in En | MEDLINE | ID: mdl-33031870

Subject(s)

Adenoviridae/immunology; BK Virus/immunology; Cytomegalovirus/immunology; Hematopoietic Stem Cell Transplantation/adverse effects; Herpesvirus 4, Human/immunology; Immunotherapy, Adoptive; T-Lymphocytes/transplantation; Virus Diseases/therapy; Adenoviridae/pathogenicity; Adenovirus Infections, Human/immunology; Adenovirus Infections, Human/therapy; Adenovirus Infections, Human/virology; Antigens, Viral/immunology; BK Virus/pathogenicity; Cells, Cultured; Cytomegalovirus/pathogenicity; Cytomegalovirus Infections/immunology; Cytomegalovirus Infections/therapy; Cytomegalovirus Infections/virology; Epstein-Barr Virus Infections/immunology; Epstein-Barr Virus Infections/therapy; Epstein-Barr Virus Infections/virology; Herpesvirus 4, Human/pathogenicity; Host-Pathogen Interactions; Humans; Immunodominant Epitopes; Lymphocyte Activation; Phenotype; Polyomavirus Infections/immunology; Polyomavirus Infections/therapy; Polyomavirus Infections/virology; T-Lymphocytes/immunology; T-Lymphocytes/virology; Tumor Virus Infections/immunology; Tumor Virus Infections/therapy; Tumor Virus Infections/virology; Virus Diseases/immunology; Virus Diseases/virology

Key words

Antigenic competition; Cytomegalovirus; Epstein-Barr virus; Multi-virus-specific T cell lines; Polyomavirus BK; T cell phenotype

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Diseases / T-Lymphocytes / Adenoviridae / Immunotherapy, Adoptive / BK Virus / Herpesvirus 4, Human / Hematopoietic Stem Cell Transplantation / Cytomegalovirus Type of study: Guideline Limits: Humans Language: En Journal: Immunol Lett Year: 2020 Document type: Article

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