'Postnatal growth during the first five years of life in SGA and AGA neonates with reduced fetal growth'.
Early Hum Dev
; 151: 105199, 2020 12.
Article
in En
| MEDLINE
| ID: mdl-33032049
ABSTRACT
BACKGROUND:
Even though a lot of research has been done on postnatal growth and the occurrence of catch-up growth in small-for-gestational age (SGA) neonates, this phenomenon has not been studied well in appropriate-for-gestational age (AGA) neonates. Postnatal catch-up growth may also occur in AGA neonates indicating a compensatory mechanism for undiagnosed intrauterine growth restriction, especially in AGA neonates with reduced fetal growth velocity.AIMS:
To describe postnatal growth during the first 5 years of life in SGA and AGA neonates and evaluating the role of fetal growth velocity in catch-up growth. STUDYDESIGN:
Retrospective study in a Dutch tertiary hospital.SUBJECTS:
740 singleton neonates, without congenital anomalies, with ultrasound fetal growth data from 20 weeks and 32 weeks of pregnancy. OUTCOMEMEASURES:
Postnatal growth measurements of height (cm) and weight (kg) from birth until five years of age. Postnatal catch-up growth defined as difference (delta) in both height and weight between 4 weeks and 3 years of age. RESULTS ANDCONCLUSIONS:
SGA neonates had a significantly lower height and weight compared to the AGA group for all available measurement moments till 3 years. The catch-up growth between the SGA and AGA groups from 4 weeks up to 3 years after birth was not different between the two groups. However, neonates with reduced fetal growth velocity had a significantly higher risk for catch-up growth in height during the first 3 years after birth. This suggests a role for fetal growth velocity measurement in predicting fetal and subsequent postnatal growth potential.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Infant, Small for Gestational Age
/
Child Development
/
Fetal Growth Retardation
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Child
/
Female
/
Humans
/
Male
/
Newborn
Language:
En
Journal:
Early Hum Dev
Year:
2020
Document type:
Article