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Trends of Opioid Use Disorder and Associated Factors in Hospitalized Patients With Arthritis.
Oladunjoye, Adeolu O; Oladunjoye, Olubunmi O; Gauvin, Jean; Yee, Maria Ruiza; Espiridion, Eduardo D.
Affiliation
  • Oladunjoye AO; Medical Critical Care, Boston Children's Hospital; Harvard Medical School, Boston, USA.
  • Oladunjoye OO; Psychiatry, Reading Hospital Tower Health, West Reading, USA.
  • Gauvin J; Internal Medicine, Reading Hospital Tower Health, West Reading, USA.
  • Yee MR; Psychiatry, Reading Hospital Tower Health, West Reading, USA.
  • Espiridion ED; Psychiatry, Philadelphia College of Osteopathic Medicine, Philadelphia, USA.
Cureus ; 12(9): e10203, 2020 Sep 02.
Article in En | MEDLINE | ID: mdl-33033680
ABSTRACT
Introduction Opioid use was primarily limited to acute pain, postsurgical care, and end of life care setting but now is the most prescribed medication for chronic pain. Arthritis is a chronic disease associated with chronic pain. Given limited options for pain relief in the patient population, these patients are often prescribed opioids and are at increased risk of opioid use disorder (OUD). Therefore, our study aimed to identify factors associated with OUD in patients with arthritis. Methods We analyzed hospitalized adult patients with arthritis with and without OUD using discharge data from National Inpatient Sample (NIS) over five years from January 1, 2010, to December 31, 2014. We looked at trends of OUD in hospitalized patients with arthritis and compared demographic and clinical characteristics of patients with and without OUD using Student's t-test and chi-square test. Multivariate analysis was also used to adjust for variables. Results A total of 21,396,252 arthritis hospitalizations were identified during the five-year study period among which 227,608 had OUD. The prevalence of OUD in arthritis hospitalization increased over the five-year period by 43%. After adjusting for other variables, mental health (OR 2.50 (2.43-2.58)), and substance use (OR 6.39 (6.14-6.66)) disorders were associated with increased odds of OUD. Conclusion The prevalence of OUD among patients with arthritis increased over the five-year study period. Mental health and substance use disorders were associated with increased odds of OUD. More studies are needed to explore alternative pain management options for arthritis patients particularly in those with mental health and substance use disorders.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Cureus Year: 2020 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Cureus Year: 2020 Document type: Article Affiliation country: United States