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Glutamate dehydrogenase as a biomarker for mitotoxicity; insights from furosemide hepatotoxicity in the mouse.
Church, Rachel J; Schomaker, Shelli J; Eaddy, J Scott; Boucher, Germaine G; Kreeger, John M; Aubrecht, Jiri; Watkins, Paul B.
Affiliation
  • Church RJ; Institute for Drug Safety Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Schomaker SJ; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Eaddy JS; Pfizer Inc., Groton, Connecticut, United States of America.
  • Boucher GG; Institute for Drug Safety Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Kreeger JM; Pfizer Inc., Groton, Connecticut, United States of America.
  • Aubrecht J; Pfizer Inc., Groton, Connecticut, United States of America.
  • Watkins PB; Pfizer Inc., Groton, Connecticut, United States of America.
PLoS One ; 15(10): e0240562, 2020.
Article in En | MEDLINE | ID: mdl-33035276
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondria, Liver / Alanine Transaminase / Chemical and Drug Induced Liver Injury / Mitophagy / Furosemide / Glutamate Dehydrogenase Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondria, Liver / Alanine Transaminase / Chemical and Drug Induced Liver Injury / Mitophagy / Furosemide / Glutamate Dehydrogenase Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States