Therapeutic alternatives in the management of osteoradionecrosis of the jaws. Systematic review.
Med Oral Patol Oral Cir Bucal
; 26(2): e195-e207, 2021 Mar 01.
Article
in En
| MEDLINE
| ID: mdl-33037800
ABSTRACT
BACKGROUND:
to systematically review the literature, comparing the healing of osteoradionecrosis (ORN) among the therapeutic alternatives surgical, pharmacological and combined. MATERIAL ANDMETHODS:
The review was organized according to the PRISMA protocol with regards to the following PICO question patients with ORN of the jaws (P=Patient); all interventions reported (I = intervention); between all therapies (C=Comparison); healing of lesions (O=outcome).RESULTS:
Surgical treatment was the most common choice (46.3%) followed by pharmacological treatment, exclusively (25.9%) or combined (26.9%). Treatment exclusively by surgical intervention seems to be most effective option, with 51.2% of the lesions healed, OR for healing of 5.7 (CI95% 1.9-16.9, p=0.002). Only 1 case (0.9%) corresponded to low level laser therapy.CONCLUSIONS:
It seems clear that early intervention with conservative surgical combined with pharmacological methods improves the prognosis of ORN.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteoradionecrosis
/
Jaw Diseases
/
Head and Neck Neoplasms
Type of study:
Etiology_studies
/
Guideline
/
Prognostic_studies
/
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Med Oral Patol Oral Cir Bucal
Journal subject:
ODONTOLOGIA
Year:
2021
Document type:
Article