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Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation.
Ruggeri Barbaro, Natalia; Van Beusecum, Justin; Xiao, Liang; do Carmo, Luciana; Pitzer, Ashley; Loperena, Roxana; Foss, Jason D; Elijovich, Fernando; Laffer, Cheryl L; Montaniel, Kim R; Galindo, Cristi L; Chen, Wei; Ao, Mingfang; Mernaugh, Raymond L; Alsouqi, Aseel; Ikizler, Talat A; Fogo, Agnes B; Moreno, Heitor; Zhao, Shilin; Davies, Sean S; Harrison, David G; Kirabo, Annet.
Affiliation
  • Ruggeri Barbaro N; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Van Beusecum J; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Xiao L; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • do Carmo L; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Pitzer A; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Loperena R; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Foss JD; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
  • Elijovich F; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Laffer CL; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Montaniel KR; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Galindo CL; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Chen W; Division of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Ao M; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Mernaugh RL; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Alsouqi A; Department of Biochemistry, Vanderbilt University, Nashville, TN, USA.
  • Ikizler TA; Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Fogo AB; Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Moreno H; Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Zhao S; Department of Intern Medicine, Faculty of Medical Sciences, Cardiovascular Pharmacology Laboratory, University of Campinas, Campinas, Brazil.
  • Davies SS; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Harrison DG; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
  • Kirabo A; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Room 536 Robinson Research Building, Nashville, TN 37232-6602, USA.
Cardiovasc Res ; 117(5): 1358-1371, 2021 04 23.
Article in En | MEDLINE | ID: mdl-33038226
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monocytes / Sodium Chloride / NADPH Oxidases / Lipid Metabolism / Lipids Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Cardiovasc Res Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monocytes / Sodium Chloride / NADPH Oxidases / Lipid Metabolism / Lipids Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Cardiovasc Res Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom