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Endothelial HMGB1 Is a Critical Regulator of LDL Transcytosis via an SREBP2-SR-BI Axis.
Ghaffari, Siavash; Jang, Erika; Naderinabi, Farnoosh; Sanwal, Rajiv; Khosraviani, Negar; Wang, Changsen; Steinberg, Benjamin E; Goldenberg, Neil M; Ikeda, Jiro; Lee, Warren L.
Affiliation
  • Ghaffari S; Keenan Centre for Biomedical Research, St. Michael's Hospital, Toronto, Canada (S.G., F.N.N., R.S., N.K., C.W., W.L.L.).
  • Jang E; Department of Laboratory Medicine and Pathobiology (E.J., R.S., W.L.L.), University of Toronto, Canada.
  • Naderinabi F; Keenan Centre for Biomedical Research, St. Michael's Hospital, Toronto, Canada (S.G., F.N.N., R.S., N.K., C.W., W.L.L.).
  • Sanwal R; Keenan Centre for Biomedical Research, St. Michael's Hospital, Toronto, Canada (S.G., F.N.N., R.S., N.K., C.W., W.L.L.).
  • Khosraviani N; Department of Laboratory Medicine and Pathobiology (E.J., R.S., W.L.L.), University of Toronto, Canada.
  • Wang C; Keenan Centre for Biomedical Research, St. Michael's Hospital, Toronto, Canada (S.G., F.N.N., R.S., N.K., C.W., W.L.L.).
  • Steinberg BE; Keenan Centre for Biomedical Research, St. Michael's Hospital, Toronto, Canada (S.G., F.N.N., R.S., N.K., C.W., W.L.L.).
  • Goldenberg NM; Hospital for Sick Children, Toronto, Canada (B.E.S., N.M.G.).
  • Ikeda J; Hospital for Sick Children, Toronto, Canada (B.E.S., N.M.G.).
  • Lee WL; Toronto General Hospital Research Institute, University Health Network, Canada (J.I.).
Arterioscler Thromb Vasc Biol ; 41(1): 200-216, 2021 01.
Article in En | MEDLINE | ID: mdl-33054399

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, LDL / HMGB1 Protein / Endothelial Cells / Atherosclerosis / Sterol Regulatory Element Binding Protein 2 / Scavenger Receptors, Class B / Transcytosis Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2021 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, LDL / HMGB1 Protein / Endothelial Cells / Atherosclerosis / Sterol Regulatory Element Binding Protein 2 / Scavenger Receptors, Class B / Transcytosis Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2021 Document type: Article Country of publication: United States