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Change in jaw occlusive power by paralysis of masseter muscle with a neuromuscular blocker: Sion's masseter muscle paralysis.
Jo, Sion; Lee, Jae Baek; Jin, Youngho; Jeong, Taeoh; Yoon, Jae Chol; Park, Boyoung.
Affiliation
  • Jo S; Department of Emergency Medicine, Chonbuk National University Hospital; Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institute of Chonbuk National University Hospital, Jeonju-si, Korea.
  • Lee JB; Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institute of Chonbuk National University Hospital; Department of Emergency Medicine, Chonbuk National University, Jeonju-si, Korea.
  • Jin Y; Department of Emergency Medicine, Chonbuk National University, Jeonju-si, Korea.
  • Jeong T; Department of Emergency Medicine, Chonbuk National University, Jeonju-si, Korea.
  • Yoon JC; Department of Emergency Medicine, Chonbuk National University, Jeonju-si, Korea.
  • Park B; National Cancer Center, National Cancer Control Institute, Goyang-si, Kyunggi-do, Korea.
Indian J Pharmacol ; 52(4): 324-330, 2020.
Article in En | MEDLINE | ID: mdl-33078734
STUDY OBJECTIVE: We aimed to determine whether jaw occlusive power decreases with the injection of neuromuscular blocking agents in masseter muscle - a method we named Sion's masseter muscle paralysis (SMP). METHODS: A randomized, placebo-controlled animal study was conducted in which researchers were blinded to group allocation. We used 12 male mongrel dogs aged 10-12 months and weighing 30-35 kg. Four groups were formed: a conventional dose (CD) group (0.004 mg/kg succinylcholine in 4 ml normal saline [NS]); a high dose (HD) group (0.04 mg/kg succinylcholine in 4 ml NS); a placebo group (4 ml NS); and no intervention group. To measure the jaw occlusive power, 1 kg weight was hung sequentially on a specifically designed device on the animal's lower jaw. At -4, -2, 0', +2, +4, +6, +8, +10, +20, and +30 min, we measured the jaw occlusive power, oxygen saturation (SpO2), and end-tidal carbon dioxide (ETCO2). RESULTS: After SMP, jaw occlusive power began to decline in CD and HD group. The arithmetical mean jaw occlusive power values at -4, -2, 0', +2, +4, +6, +8, and +10 min were 9.7, 9.7, 9.7, 8.7, 8.3, 7.3, 6.7, and 6.3 kgw in the CD group and 9.7, 9.3, 8.7, 8.0, 6.7, 5.0, 5.0, and 5.3 kgw in the HD group. No abnormalities in SpO2or ETCO2were detected. CONCLUSION: Jaw occlusive power was decreased after SMP with succinylcholine, without inducing respiratory complication.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paralysis / Succinylcholine / Masseter Muscle / Muscle Contraction / Neuromuscular Blocking Agents Limits: Animals Language: En Journal: Indian J Pharmacol Year: 2020 Document type: Article Country of publication: India

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paralysis / Succinylcholine / Masseter Muscle / Muscle Contraction / Neuromuscular Blocking Agents Limits: Animals Language: En Journal: Indian J Pharmacol Year: 2020 Document type: Article Country of publication: India