The effect of charge on the uptake and resistance to reduction of platinum(IV) complexes in human serum and whole blood models.

Chen, Catherine K J; Gui, Xiao; Kappen, Peter; Renfrew, Anna K; Hambley, Trevor W

Chen, Catherine K J; Gui, Xiao; Kappen, Peter; Renfrew, Anna K; Hambley, Trevor W.

Affiliation

Chen CKJ; School of Chemistry, The University of Sydney, NSW, Australia. trevor.hambley@sydney.edu.au.
Gui X; School of Chemistry, The University of Sydney, NSW, Australia. trevor.hambley@sydney.edu.au.
Kappen P; Australian Synchrotron, ANSTO, 800 Blackburn Road, Clayton 3168, Victoria, Australia.
Renfrew AK; School of Chemistry, The University of Sydney, NSW, Australia. trevor.hambley@sydney.edu.au.
Hambley TW; School of Chemistry, The University of Sydney, NSW, Australia. trevor.hambley@sydney.edu.au.

Metallomics ; 12(10): 1599-1615, 2020 10 21.

Article in En | MEDLINE | ID: mdl-33084707

Subject(s)

Antineoplastic Agents/chemistry; Antineoplastic Agents/pharmacokinetics; Ascorbic Acid/metabolism; Organoplatinum Compounds/chemistry; Organoplatinum Compounds/pharmacokinetics; Antineoplastic Agents/metabolism; Antineoplastic Agents/pharmacology; Cell Line, Tumor; Humans; Neoplasms/drug therapy; Neoplasms/metabolism; Organoplatinum Compounds/metabolism; Organoplatinum Compounds/pharmacology; Oxidation-Reduction; Prodrugs/chemistry; Prodrugs/metabolism; Prodrugs/pharmacokinetics; Prodrugs/pharmacology; Serum/metabolism; Static Electricity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organoplatinum Compounds / Ascorbic Acid / Antineoplastic Agents Limits: Humans Language: En Journal: Metallomics Journal subject: BIOQUIMICA Year: 2020 Document type: Article Affiliation country: Australia Country of publication: United kingdom

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