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Atipamezole, a specific α2A antagonist, suppresses spike-and-wave discharges and alters Ca2⁺ /calmodulin-dependent protein kinase II in the thalamus of genetic absence epilepsy rats.
Yavuz, Melis; Aydin, Banu; Çarçak, Nihan; Akman, Özlem; Raci Yananli, Hasan; Onat, Filiz.
Affiliation
  • Yavuz M; Department of Pharmacology, Faculty of Pharmacy, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
  • Aydin B; Department of Medical Pharmacology, Faculty of Medicine, Marmara University, Istanbul, Turkey.
  • Çarçak N; Department of Biophysics, Faculty of Medicine, Marmara University, Istanbul, Turkey.
  • Akman Ö; Department of Pharmacology, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey.
  • Raci Yananli H; Department of Physiology, Faculty of Medicine, Demiroglu Bilim University, Istanbul, Turkey.
  • Onat F; Department of Medical Pharmacology, Faculty of Medicine, Marmara University, Istanbul, Turkey.
Epilepsia ; 61(12): 2825-2835, 2020 12.
Article in En | MEDLINE | ID: mdl-33098125
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thalamus / Epilepsy, Absence / Calcium-Calmodulin-Dependent Protein Kinase Type 2 / Adrenergic alpha-2 Receptor Antagonists / Imidazoles / Anticonvulsants Limits: Animals Language: En Journal: Epilepsia Year: 2020 Document type: Article Affiliation country: Turkey Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thalamus / Epilepsy, Absence / Calcium-Calmodulin-Dependent Protein Kinase Type 2 / Adrenergic alpha-2 Receptor Antagonists / Imidazoles / Anticonvulsants Limits: Animals Language: En Journal: Epilepsia Year: 2020 Document type: Article Affiliation country: Turkey Country of publication: United States