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Local delivery of CAR T cells targeting fibroblast activation protein is safe in patients with pleural mesothelioma: first report of FAPME, a phase I clinical trial.
Hiltbrunner, S; Britschgi, C; Schuberth, P; Bankel, L; Nguyen-Kim, T D L; Gulati, P; Weder, W; Opitz, I; Lauk, O; Caviezel, C; Bachmann, H; Tabor, A; Schröder, P; Knuth, A; Münz, C; Stahel, R; Boyman, O; Renner, C; Petrausch, U; Curioni-Fontecedro, A.
Affiliation
  • Hiltbrunner S; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland; Comprehensive Cancer Center Zurich, University of Zurich, Zurich, Switzerland.
  • Britschgi C; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland; Comprehensive Cancer Center Zurich, University of Zurich, Zurich, Switzerland.
  • Schuberth P; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland; Comprehensive Cancer Center Zurich, University of Zurich, Zurich, Switzerland.
  • Bankel L; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland; Comprehensive Cancer Center Zurich, University of Zurich, Zurich, Switzerland.
  • Nguyen-Kim TDL; Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland.
  • Gulati P; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
  • Weder W; Department of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland.
  • Opitz I; Department of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland.
  • Lauk O; Department of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.
  • Caviezel C; Department of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.
  • Bachmann H; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland; Comprehensive Cancer Center Zurich, University of Zurich, Zurich, Switzerland.
  • Tabor A; Biontech Innovative Manufacturing Services, Idar-Oberstein, Germany.
  • Schröder P; Biontech Innovative Manufacturing Services, Idar-Oberstein, Germany.
  • Knuth A; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland; Comprehensive Cancer Center Zurich, University of Zurich, Zurich, Switzerland.
  • Münz C; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
  • Stahel R; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland; Comprehensive Cancer Center Zurich, University of Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland.
  • Boyman O; Department of Immunology, University Hospital Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland.
  • Renner C; Faculty of Medicine, University of Basel, Basel, Switzerland; Onkozentrum Zürich, Swiss Tumor Immunology Institute, Zurich, Switzerland.
  • Petrausch U; Faculty of Medicine, University of Zurich, Zurich, Switzerland; Onkozentrum Zürich, Swiss Tumor Immunology Institute, Zurich, Switzerland.
  • Curioni-Fontecedro A; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland; Comprehensive Cancer Center Zurich, University of Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland. Electronic address: alessandra.curioni@usz.ch.
Ann Oncol ; 32(1): 120-121, 2021 01.
Article in En | MEDLINE | ID: mdl-33098996
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pleural Neoplasms / Mesothelioma, Malignant / Lung Neoplasms / Mesothelioma Limits: Humans Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2021 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pleural Neoplasms / Mesothelioma, Malignant / Lung Neoplasms / Mesothelioma Limits: Humans Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2021 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom