Mitochondrial Dysfunction Accelerates Ageing.
Immunometabolism
; 2(4): e200035, 2020 Oct 16.
Article
in En
| MEDLINE
| ID: mdl-33101729
ABSTRACT
We review here the seminal findings of Desdin-Mico et al. showing that T cells with dysfunctional mitochondria induce multimorbity and premature senescence, due to mitochondrial transcription factor A (TFAM). They add further weight to the idea that targeting immunometabolism could be beneficial in combating the detrimental effects of age-related disease.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Immunometabolism
Year:
2020
Document type:
Article
Affiliation country:
United kingdom