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Anti-Angiogenic Properties of Ginsenoside Rg3.
Nakhjavani, Maryam; Smith, Eric; Townsend, Amanda R; Price, Timothy J; Hardingham, Jennifer E.
Affiliation
  • Nakhjavani M; Molecular Oncology, Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, Woodville South, SA 5011, Australia.
  • Smith E; Adelaide Medical School, University of Adelaide, Adelaide, SA 5005, Australia.
  • Townsend AR; Molecular Oncology, Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, Woodville South, SA 5011, Australia.
  • Price TJ; Adelaide Medical School, University of Adelaide, Adelaide, SA 5005, Australia.
  • Hardingham JE; Adelaide Medical School, University of Adelaide, Adelaide, SA 5005, Australia.
Molecules ; 25(21)2020 Oct 23.
Article in En | MEDLINE | ID: mdl-33113992
Ginsenoside Rg3 (Rg3) is a member of the ginsenoside family of chemicals extracted from Panax ginseng. Like other ginsenosides, Rg3 has two epimers: 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3). Rg3 is an intriguing molecule due to its anti-cancer properties. One facet of the anti-cancer properties of Rg3 is the anti-angiogenic action. This review describes the controversies on the effects and effective dose range of Rg3, summarizes the evidence on the efficacy of Rg3 on angiogenesis, and raises the possibility that Rg3 is a prodrug.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Angiogenesis Inhibitors / Ginsenosides Limits: Animals / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2020 Document type: Article Affiliation country: Australia Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Angiogenesis Inhibitors / Ginsenosides Limits: Animals / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2020 Document type: Article Affiliation country: Australia Country of publication: Switzerland