Targeting the Cholecystokinin Receptor: A Novel Approach for Treatment and Prevention of Hepatocellular Cancer.

Gay, Martha D; Safronenka, Anita; Cao, Hong; Liu, Felice H; Malchiodi, Zoe X; Tucker, Robin D; Kroemer, Alexander; Shivapurkar, Narayan; Smith, Jill P

Gay, Martha D; Safronenka, Anita; Cao, Hong; Liu, Felice H; Malchiodi, Zoe X; Tucker, Robin D; Kroemer, Alexander; Shivapurkar, Narayan; Smith, Jill P.

Affiliation

Gay MD; Department of Medicine, Georgetown University College of Medicine, Washington, DC.
Safronenka A; Department of Medicine, Georgetown University College of Medicine, Washington, DC.
Cao H; Department of Medicine, Georgetown University College of Medicine, Washington, DC.
Liu FH; Department of Medicine, Georgetown University College of Medicine, Washington, DC.
Malchiodi ZX; Department of Oncology, Georgetown University College of Medicine, Washington, DC.
Tucker RD; Department of Pathology, Georgetown University College of Medicine, Washington, DC.
Kroemer A; MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington DC.
Shivapurkar N; Department of Medicine, Georgetown University College of Medicine, Washington, DC.
Smith JP; Department of Medicine, Georgetown University College of Medicine, Washington, DC. jps261@georgetown.edu.

Cancer Prev Res (Phila) ; 14(1): 17-30, 2021 01.

Article in En | MEDLINE | ID: mdl-33115780

Subject(s)

Carcinoma, Hepatocellular/prevention & control; Liver Neoplasms/prevention & control; Non-alcoholic Fatty Liver Disease/drug therapy; Proglumide/pharmacology; Receptor, Cholecystokinin B/antagonists & inhibitors; Animals; Carcinoma, Hepatocellular/pathology; Cell Line, Tumor; Chemokines, CC/genetics; Chemokines, CC/metabolism; Cholecystokinin/metabolism; Diet, High-Fat/adverse effects; Disease Models, Animal; Female; Gene Knockout Techniques; Hepatic Stellate Cells/drug effects; Hepatic Stellate Cells/pathology; Humans; Liver/cytology; Liver/drug effects; Liver/pathology; Liver Neoplasms/pathology; Male; Mice; Non-alcoholic Fatty Liver Disease/etiology; Non-alcoholic Fatty Liver Disease/pathology; Proglumide/therapeutic use; Receptor, Cholecystokinin B/genetics; Receptor, Cholecystokinin B/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proglumide / Carcinoma, Hepatocellular / Receptor, Cholecystokinin B / Non-alcoholic Fatty Liver Disease / Liver Neoplasms Type of study: Etiology_studies Limits: Animals / Female / Humans / Male Language: En Journal: Cancer Prev Res (Phila) Journal subject: NEOPLASIAS Year: 2021 Document type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google