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SIK2 represses AKT/GSK3ß/ß-catenin signaling and suppresses gastric cancer by inhibiting autophagic degradation of protein phosphatases.
Dai, Xiao-Man; Zhang, Yan-Hui; Lin, Xiao-Han; Huang, Xiao-Xing; Zhang, Yi; Xue, Chao-Rong; Chen, Wan-Nan; Ye, Jian-Xin; Lin, Xin-Jian; Lin, Xu.
Affiliation
  • Dai XM; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Zhang YH; Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fuzhou, China.
  • Lin XH; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Huang XX; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Zhang Y; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Xue CR; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Chen WN; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Ye JX; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Lin XJ; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, China.
  • Lin X; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Mol Oncol ; 15(1): 228-245, 2021 01.
Article in En | MEDLINE | ID: mdl-33128264
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Stomach Neoplasms / Signal Transduction / Protein Serine-Threonine Kinases / Phosphoprotein Phosphatases / Protein Phosphatase 2 / Proteolysis Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male / Middle aged Language: En Journal: Mol Oncol Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2021 Document type: Article Affiliation country: China Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Stomach Neoplasms / Signal Transduction / Protein Serine-Threonine Kinases / Phosphoprotein Phosphatases / Protein Phosphatase 2 / Proteolysis Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male / Middle aged Language: En Journal: Mol Oncol Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2021 Document type: Article Affiliation country: China Country of publication: United States