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Bioactive sesquiterpene coumarins from the resin of Ferula sinkiangensis targeted on over-activation of microglia.
Guo, Tingting; Zhou, Di; Yang, Yanqiu; Zhang, Xueni; Chen, Gang; Lin, Bin; Sun, Yu; Ni, Hui; Liu, Jingyu; Hou, Yue; Li, Ning.
Affiliation
  • Guo T; School of Traditional Chinese Materia Medica, Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning Province, China.
  • Zhou D; School of Traditional Chinese Materia Medica, Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning Province, China.
  • Yang Y; College of Life and Health Sciences, Northeastern University, Shenyang 110004, China; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin, China.
  • Zhang X; School of Traditional Chinese Materia Medica, Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning Province, China.
  • Chen G; School of Traditional Chinese Materia Medica, Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning Province, China.
  • Lin B; School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Sun Y; XinJiang Institute of Chinese Materia Medica and Ethnodrug, Urumqi 830002, China.
  • Ni H; XinJiang Institute of Chinese Materia Medica and Ethnodrug, Urumqi 830002, China.
  • Liu J; College of Life and Health Sciences, Northeastern University, Shenyang 110004, China; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin, China.
  • Hou Y; College of Life and Health Sciences, Northeastern University, Shenyang 110004, China; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin, China. Electronic address: houyue@mail.neu.edu.cn.
  • Li N; School of Traditional Chinese Materia Medica, Key Laboratory of Computational Chemistry-Based Natural Antitumor Drug Research & Development, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning Province, China. Electronic address: liningsypharm@163.com.
Bioorg Chem ; 104: 104338, 2020 11.
Article in En | MEDLINE | ID: mdl-33142410
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Resins, Plant / Sesquiterpenes / Microglia / Coumarins / Ferula / Anti-Inflammatory Agents Limits: Animals Language: En Journal: Bioorg Chem Year: 2020 Document type: Article Affiliation country: China Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Resins, Plant / Sesquiterpenes / Microglia / Coumarins / Ferula / Anti-Inflammatory Agents Limits: Animals Language: En Journal: Bioorg Chem Year: 2020 Document type: Article Affiliation country: China Country of publication: United States