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GSK669, a NOD2 receptor antagonist, inhibits thrombosis and oxidative stress via targeting platelet GPVI.
Pan, Guanxing; Chang, Lin; Zhang, Jianjun; Liu, Yangyang; Hu, Liang; Zhang, Si; Zhang, Jian; Qiao, Jianlin; Jakopin, Ziga; Hu, Hu; Dong, Jianzeng; Ding, Zhongren.
Affiliation
  • Pan G; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  • Chang L; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  • Zhang J; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  • Liu Y; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450018, China.
  • Hu L; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450018, China.
  • Zhang S; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  • Zhang J; Department of Pathophysiology, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China.
  • Qiao J; Department of Hematology, Blood Disease Institute, Xuzhou Medical University, Xuzhou 221004, China.
  • Jakopin Z; Faculty of Pharmacy, University of Ljubljana, Askerceva 7, SI-1000 Ljubljana, Slovenia.
  • Hu H; Department of Pathophysiology, Zhejiang University School of Medicine, Hangzhou 310012, China.
  • Dong J; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450018, China.
  • Ding Z; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450018, China.
Biochem Pharmacol ; 183: 114315, 2021 01.
Article in En | MEDLINE | ID: mdl-33152345
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Blood Platelets / Platelet Aggregation Inhibitors / Platelet Membrane Glycoproteins / Oxidative Stress / Nod2 Signaling Adaptor Protein Limits: Animals Language: En Journal: Biochem Pharmacol Year: 2021 Document type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Blood Platelets / Platelet Aggregation Inhibitors / Platelet Membrane Glycoproteins / Oxidative Stress / Nod2 Signaling Adaptor Protein Limits: Animals Language: En Journal: Biochem Pharmacol Year: 2021 Document type: Article Affiliation country: China