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Optimized radiological alert thresholds based on device dosimetric information and peak skin dose in vascular fluoroscopically guided intervention.
Sas, Nicolas; Magnier, Florian; Pouget, Eléonore; Dedieu, Véronique; Guersen, Joël; Chabrot, Pascal; Boyer, Louis; Cassagnes, Lucie.
Affiliation
  • Sas N; Plateforme régionale de physique médicale, Centre de Lutte Contre le Centre Jean Perrin, 58 Rue Montalembert, 63011, Clermont-Ferrand Cedex 1, France. nicolas.sas@clermont.unicancer.fr.
  • Magnier F; Plateforme régionale de physique médicale, Centre de Lutte Contre le Centre Jean Perrin, 58 Rue Montalembert, 63011, Clermont-Ferrand Cedex 1, France.
  • Pouget E; Service de radiothérapie, Centre Saint Jean, 18230, Bourges, France.
  • Dedieu V; Plateforme régionale de physique médicale, Centre de Lutte Contre le Centre Jean Perrin, 58 Rue Montalembert, 63011, Clermont-Ferrand Cedex 1, France.
  • Guersen J; Plateforme régionale de physique médicale, Centre de Lutte Contre le Centre Jean Perrin, 58 Rue Montalembert, 63011, Clermont-Ferrand Cedex 1, France.
  • Chabrot P; Pôle Interhospitalier d'Imagerie Diagnostique et de Radiologie Interventionnelle, CHU, 63003, Clermont-Ferrand, France.
  • Boyer L; Pôle Interhospitalier d'Imagerie Diagnostique et de Radiologie Interventionnelle, CHU, 63003, Clermont-Ferrand, France.
  • Cassagnes L; Pôle Interhospitalier d'Imagerie Diagnostique et de Radiologie Interventionnelle, CHU, 63003, Clermont-Ferrand, France.
Eur Radiol ; 31(5): 3027-3034, 2021 May.
Article in En | MEDLINE | ID: mdl-33156387
ABSTRACT

OBJECTIVES:

The National Council on Radiation Protection (NCRP) report no. 168 recommended that during fluoroscopically guided interventions (FGIs), each patient should be monitored when one of the following thresholds is reached an air kerma > 5 Gy, a kerma area product (KAP) > 500 Gy.cm2, a fluoroscopy time > 60 min, or a peak skin dose (PSD) > 3 Gy. Whereas PSD is the most accurate metric regarding the prevention of radiological risks, it remains the most difficult parameter to assess. We aimed to evaluate the relevance of the other, more accessible metrics and propose new optimized threshold (OT) for improved patient follow-up.

METHODS:

Overall, 108 patients who underwent FGI in which at least one NCRP threshold was reached and PSD was measured were considered. The correlation between all metrics was assessed using principal component analysis (PCA). ROC curves and the sensitivity/specificity of both NCRP and OT to predict PSD > 3 Gy were evaluated.

RESULTS:

The PCA shows that FGI can be decomposed with two components based on time and dose variables. Only KAP and kerma were correlated with PSD. The overall sensitivity and specificity of the new OT regarding KAP (67.6/93.0), kerma (97.3/81.7), and time (62.2/62.0) were better compared with NCRP thresholds (97.3/16.9, 40.5/95.4, and 21.6/74.7).

CONCLUSIONS:

This study shows that fluoroscopy time is not a relevant metric when used to predict PSDs > 3 Gy. By adapting KAP and kerma thresholds to predict PSD over 3 Gy, patient follow-ups following vascular FGI can be improved. KEY POINTS • In vascular fluoroscopically guided interventions, principal component analysis demonstrates that between fluoroscopy time, KAP, and kerma, only the two last were correlated to the peak skin dose. • Optimized thresholds replacing NRCP ones obtained with ROC curves analysis were 85,451 µGy.cm2, 2938 mGy, and 41 min for KAP, kerma, and fluoroscopy time respectively. • Improvements to trigger patient follow-up after vascular fluoroscopically guided interventions may be obtained by using the optimized thresholds.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation Protection / Radiography, Interventional Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur Radiol Journal subject: RADIOLOGIA Year: 2021 Document type: Article Affiliation country: France

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation Protection / Radiography, Interventional Type of study: Prognostic_studies Limits: Humans Language: En Journal: Eur Radiol Journal subject: RADIOLOGIA Year: 2021 Document type: Article Affiliation country: France