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Paclitaxel-Loaded Colloidal Silica and TPGS-Based Solid Self-Emulsifying System Interferes Akt/mTOR Pathway in MDA-MB-231 and Demonstrates Anti-tumor Effect in Syngeneic Mammary Tumors.
Meher, Jaya Gopal; Dixit, Shivani; Singh, Yuvraj; Pawar, Vivek K; Konwar, Rituraj; Saklani, Ravi; Chourasia, Manish K.
Affiliation
  • Meher JG; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.
  • Dixit S; Endocrinology Division, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.
  • Singh Y; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.
  • Pawar VK; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.
  • Konwar R; Endocrinology Division, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.
  • Saklani R; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India.
  • Chourasia MK; Pharmaceutics and Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow, UP, 226031, India. manish_chourasia@cdri.res.in.
AAPS PharmSciTech ; 21(8): 313, 2020 Nov 09.
Article in En | MEDLINE | ID: mdl-33165766
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vitamin E / Mammary Neoplasms, Animal / Paclitaxel / Colloids / Silicon Dioxide / Proto-Oncogene Proteins c-akt / TOR Serine-Threonine Kinases / Antineoplastic Agents, Phytogenic Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: AAPS PharmSciTech Journal subject: FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: India Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vitamin E / Mammary Neoplasms, Animal / Paclitaxel / Colloids / Silicon Dioxide / Proto-Oncogene Proteins c-akt / TOR Serine-Threonine Kinases / Antineoplastic Agents, Phytogenic Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: AAPS PharmSciTech Journal subject: FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: India Country of publication: United States