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'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19.
Mandal, Swapna; Barnett, Joseph; Brill, Simon E; Brown, Jeremy S; Denneny, Emma K; Hare, Samanjit S; Heightman, Melissa; Hillman, Toby E; Jacob, Joseph; Jarvis, Hannah C; Lipman, Marc C I; Naidu, Sindhu B; Nair, Arjun; Porter, Joanna C; Tomlinson, Gillian S; Hurst, John R.
Affiliation
  • Mandal S; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK.
  • Barnett J; Department of Radiology, Royal Free London NHS Foundation Trust, London, UK.
  • Brill SE; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK.
  • Brown JS; UCL Respiratory, University College London, London, UK.
  • Denneny EK; Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK.
  • Hare SS; Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK.
  • Heightman M; Department of Radiology, Royal Free London NHS Foundation Trust, London, UK.
  • Hillman TE; Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK.
  • Jacob J; Respiratory Medicine, University College London Hospitals NHS Foundation Trust, London, UK.
  • Jarvis HC; Centre for Medical Image Computing, University College London, London, UK.
  • Lipman MCI; Department of Radiology, University College London Hospitals NHS Foundation Trust, London, UK.
  • Naidu SB; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK.
  • Nair A; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK.
  • Porter JC; UCL Respiratory, University College London, London, UK.
  • Tomlinson GS; Respiratory Medicine, Royal Free London NHS Foundation Trust, London, UK.
  • Hurst JR; Department of Radiology, University College London Hospitals NHS Foundation Trust, London, UK.
Thorax ; 76(4): 396-398, 2021 04.
Article in En | MEDLINE | ID: mdl-33172844
Large numbers of people are being discharged from hospital following COVID-19 without assessment of recovery. In 384 patients (mean age 59.9 years; 62% male) followed a median 54 days post discharge, 53% reported persistent breathlessness, 34% cough and 69% fatigue. 14.6% had depression. In those discharged with elevated biomarkers, 30.1% and 9.5% had persistently elevated d-dimer and C reactive protein, respectively. 38% of chest radiographs remained abnormal with 9% deteriorating. Systematic follow-up after hospitalisation with COVID-19 identifies the trajectory of physical and psychological symptom burden, recovery of blood biomarkers and imaging which could be used to inform the need for rehabilitation and/or further investigation.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diagnostic Imaging / Pandemics / SARS-CoV-2 / COVID-19 / Lung Type of study: Clinical_trials / Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Thorax Year: 2021 Document type: Article Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diagnostic Imaging / Pandemics / SARS-CoV-2 / COVID-19 / Lung Type of study: Clinical_trials / Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Thorax Year: 2021 Document type: Article Country of publication: United kingdom