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Therapeutics potentiating microglial p21-Nrf2 axis can rescue neurodegeneration caused by neuroinflammation.
Nakano-Kobayashi, A; Fukumoto, A; Morizane, A; Nguyen, D T; Le, T M; Hashida, K; Hosoya, T; Takahashi, R; Takahashi, J; Hori, O; Hagiwara, M.
Affiliation
  • Nakano-Kobayashi A; Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. kobayashi.akiko.5e@kyoto-u.ac.jp hagiwara.masatoshi.8c@kyoto-u.ac.jp.
  • Fukumoto A; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.
  • Morizane A; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.
  • Nguyen DT; Department of Neuroanatomy, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan.
  • Le TM; Department of Neuroanatomy, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan.
  • Hashida K; Department of Neuroanatomy, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan.
  • Hosoya T; Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan.
  • Takahashi R; Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Takahashi J; Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.
  • Hori O; Department of Neuroanatomy, Graduate School of Medical Sciences, Kanazawa University, Ishikawa, Japan.
  • Hagiwara M; Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. kobayashi.akiko.5e@kyoto-u.ac.jp hagiwara.masatoshi.8c@kyoto-u.ac.jp.
Sci Adv ; 6(46)2020 11.
Article in En | MEDLINE | ID: mdl-33188020
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / Neurodegenerative Diseases Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Sci Adv Year: 2020 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / Neurodegenerative Diseases Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Sci Adv Year: 2020 Document type: Article