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A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles.
Kurzawa, Nils; Becher, Isabelle; Sridharan, Sindhuja; Franken, Holger; Mateus, André; Anders, Simon; Bantscheff, Marcus; Huber, Wolfgang; Savitski, Mikhail M.
Affiliation
  • Kurzawa N; European Molecular Biology Laboratory, Genome Biology Unit, Meyerhofstrasse 1, Heidelberg, 69117, Germany.
  • Becher I; Faculty of Biosciences, Heidelberg University, Heidelberg, 69120, Germany.
  • Sridharan S; European Molecular Biology Laboratory, Genome Biology Unit, Meyerhofstrasse 1, Heidelberg, 69117, Germany.
  • Franken H; European Molecular Biology Laboratory, Genome Biology Unit, Meyerhofstrasse 1, Heidelberg, 69117, Germany.
  • Mateus A; Cellzome GmbH, GlaxoSmithKline, Meyerhofstrasse 1, Heidelberg, 69117, Germany.
  • Anders S; Cellzome GmbH, GlaxoSmithKline, Meyerhofstrasse 1, Heidelberg, 69117, Germany.
  • Bantscheff M; European Molecular Biology Laboratory, Genome Biology Unit, Meyerhofstrasse 1, Heidelberg, 69117, Germany.
  • Huber W; Center for Molecular Biology of Heidelberg University (ZMBH), Im Neuenheimer Feld 282, Heidelberg, 69120, Germany.
  • Savitski MM; Cellzome GmbH, GlaxoSmithKline, Meyerhofstrasse 1, Heidelberg, 69117, Germany. marcus.x.bantscheff@gsk.com.
Nat Commun ; 11(1): 5783, 2020 11 13.
Article in En | MEDLINE | ID: mdl-33188197
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Temperature / Computational Biology / Proteome / Proteomics Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: Germany Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Temperature / Computational Biology / Proteome / Proteomics Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: Germany Country of publication: United kingdom