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Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA.
Yuan, Shuai; Peng, Lei; Park, Jonathan J; Hu, Yingxia; Devarkar, Swapnil C; Dong, Matthew B; Shen, Qi; Wu, Shenping; Chen, Sidi; Lomakin, Ivan B; Xiong, Yong.
Affiliation
  • Yuan S; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
  • Peng L; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA; Systems Biology Institute, Yale University, West Haven, CT 06516, USA.
  • Park JJ; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA; Systems Biology Institute, Yale University, West Haven, CT 06516, USA.
  • Hu Y; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
  • Devarkar SC; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
  • Dong MB; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA; Systems Biology Institute, Yale University, West Haven, CT 06516, USA.
  • Shen Q; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
  • Wu S; Department of Pharmacology, Yale University, West Haven, CT 06516, USA.
  • Chen S; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA; Systems Biology Institute, Yale University, West Haven, CT 06516, USA. Electronic address: sidi.chen@yale.edu.
  • Lomakin IB; Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: ivan.lomakin@yale.edu.
  • Xiong Y; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA. Electronic address: yong.xiong@yale.edu.
Mol Cell ; 80(6): 1055-1066.e6, 2020 12 17.
Article in En | MEDLINE | ID: mdl-33188728
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / RNA, Messenger / RNA, Viral / Viral Nonstructural Proteins / SARS-CoV-2 / COVID-19 Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / RNA, Messenger / RNA, Viral / Viral Nonstructural Proteins / SARS-CoV-2 / COVID-19 Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States