Notch signaling mitigates chemotherapy toxicity by accelerating hematopoietic stem cells proliferation via c-Myc.

Chen, Juanjuan; Dong, Yan; Peng, Jie; Zhang, Jian; Gao, Xiaotong; Lu, Aili; Shen, Chunlin

Chen, Juanjuan; Dong, Yan; Peng, Jie; Zhang, Jian; Gao, Xiaotong; Lu, Aili; Shen, Chunlin.

Affiliation

Chen J; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University Guangzhou, China.
Dong Y; Department of Oncology and Hematology, 421th Hospital of Chinese People's Liberation Army Guangzhou, China.
Peng J; Department of Hematology, Tangdu Hospital, Fourth Military Medical University Xi'an, China.
Zhang J; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University Guangzhou, China.
Gao X; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University Guangzhou, China.
Lu A; Department of Hematology, Tangdu Hospital, Fourth Military Medical University Xi'an, China.
Shen C; State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University Guangzhou, China.

Am J Transl Res ; 12(10): 6723-6739, 2020.

Article in En | MEDLINE | ID: mdl-33194068

Key words

Hematopoietic stem cells regeneration; c-Myc; delta-like 1; notch signaling; proliferation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Am J Transl Res Year: 2020 Document type: Article Affiliation country: China Country of publication: United States

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