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[Retrospective cross-sectional study based on nationwide data of drug prescriptions and contractional data of outpatient offices regarding Morbus Wilson's disease]. / Retrospektive Querschnittsstudie von bundesweiten Arzneiverordnungsdaten und vertragsärztlichen Abrechnungsdaten von Morbus Wilson.
Janka, Simone-Svea; Bätzing, Jörg; Laux, Gunter; Holstiege, Jakob; Wahler, Steffen; Merle, Uta; Mehrabi, Arianeb; Mohr, Isabelle; Weiss, Karl Heinz; Mieth, Markus.
Affiliation
  • Janka SS; Abteilung Allgemeinmedizin und Versorgungsforschung, Universitätsklinikum Heidelberg, Heidelberg, Germany.
  • Bätzing J; Zentralinstitut für die kassenärztliche Versorgung in der Bundesrepublik Deutschland, Berlin, Germany.
  • Laux G; Abteilung Allgemeinmedizin und Versorgungsforschung, Universitätsklinikum Heidelberg, Heidelberg, Germany.
  • Holstiege J; Zentralinstitut für die kassenärztliche Versorgung in der Bundesrepublik Deutschland, Berlin, Germany.
  • Wahler S; Institut für Molekulare Muskuloskelettale Forschung, Klinikum der Universität München, Germany.
  • Merle U; Medizinische Klinik IV, Klinik für Gastroenterologie, Infektionskrankheiten, Vergiftungen, Universitätsklinikum Heidelberg, Heidelberg, Germany.
  • Mehrabi A; Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Chirurgische Universitätsklinik Heidelberg, Heidelberg, Germany.
  • Mohr I; Medizinische Klinik IV, Klinik für Gastroenterologie, Infektionskrankheiten, Vergiftungen, Universitätsklinikum Heidelberg, Heidelberg, Germany.
  • Weiss KH; Medizinische Klinik IV, Klinik für Gastroenterologie, Infektionskrankheiten, Vergiftungen, Universitätsklinikum Heidelberg, Heidelberg, Germany.
  • Mieth M; Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Chirurgische Universitätsklinik Heidelberg, Heidelberg, Germany.
Z Gastroenterol ; 58(11): 1054-1064, 2020 Nov.
Article in De | MEDLINE | ID: mdl-33197948
ABSTRACT

INTRODUCTION:

In this article, the prevalence of the Morbus Wilson disease in Germany is determined. This is based on nationwide data of drug prescriptions and contractional data of outpatient offices. The prevalence is set in ratio to the found prevalence of prescriptions in Germany.

METHOD:

The descriptive evaluation is based on the database of the Central Research Institute of Ambulatory Health Care (Zi) in Germany. Additionally, data of the Federal Office of Statistics regarding inpatient treatment are available.

RESULTS:

It can be seen that there is a notable difference between the prevalence of patients undergoing therapy and the patients with verified diagnoses. In total, prevalence is increasing. The incidence on hand and the given dynamic of the patient population could indicate that, possibly, there is an increased rate of misdiagnosis in the first year of diagnosis. According to data, the hepatic form is the more often diagnosed form. The human genetic diagnostic increases, on average, are most distinct. ATTRIBUTES Wilson Disease, Prevalence, Incidence, Trientine, Trientintetrahydrochlorid, D-Penicillamin, Zinc acetat, Zinc.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Penicillamine / Drug Prescriptions / Trientine / Zinc / Hepatolenticular Degeneration Type of study: Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Humans Country/Region as subject: Europa Language: De Journal: Z Gastroenterol Year: 2020 Document type: Article Affiliation country: Germany

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Penicillamine / Drug Prescriptions / Trientine / Zinc / Hepatolenticular Degeneration Type of study: Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Humans Country/Region as subject: Europa Language: De Journal: Z Gastroenterol Year: 2020 Document type: Article Affiliation country: Germany