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Disrupting polycystin-2 EF hand Ca2+ affinity does not alter channel function or contribute to polycystic kidney disease.
Vien, Thuy N; Ng, Leo C T; Smith, Jessica M; Dong, Ke; Krappitz, Matteus; Gainullin, Vladimir G; Fedeles, Sorin; Harris, Peter C; Somlo, Stefan; DeCaen, Paul G.
Affiliation
  • Vien TN; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Ng LCT; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Smith JM; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA.
  • Dong K; Departments of Internal Medicine and Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Krappitz M; Departments of Internal Medicine and Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Gainullin VG; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA.
  • Fedeles S; Departments of Internal Medicine and Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Harris PC; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA.
  • Somlo S; Departments of Internal Medicine and Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
  • DeCaen PG; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA paul.decaen@northwestern.edu.
J Cell Sci ; 133(24)2020 12 24.
Article in En | MEDLINE | ID: mdl-33199522
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycystic Kidney, Autosomal Dominant / Polycystic Kidney Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Cell Sci Year: 2020 Document type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycystic Kidney, Autosomal Dominant / Polycystic Kidney Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Cell Sci Year: 2020 Document type: Article Affiliation country: United States