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Prostate-Specific Membrane Antigen Uptake in a Peripheral Nerve and Respective Ganglia on 68Ga-Prostate-Specific Membrane Antigen-HBED-CC PET/CT.
Mettler, Jasmin; Drzezga, Alexander; Dietlein, Markus; Hucho, Tim; Kobe, Carsten.
Affiliation
  • Mettler J; From the Department for Nuclear Medicine, Faculty of Medicine and University Hospital of Cologne, Center for Integrated, Oncology Aachen Bonn Cologne Duesseldorf.
  • Drzezga A; From the Department for Nuclear Medicine, Faculty of Medicine and University Hospital of Cologne, Center for Integrated, Oncology Aachen Bonn Cologne Duesseldorf.
  • Dietlein M; From the Department for Nuclear Medicine, Faculty of Medicine and University Hospital of Cologne, Center for Integrated, Oncology Aachen Bonn Cologne Duesseldorf.
  • Hucho T; Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Kobe C; From the Department for Nuclear Medicine, Faculty of Medicine and University Hospital of Cologne, Center for Integrated, Oncology Aachen Bonn Cologne Duesseldorf.
Clin Nucl Med ; 46(1): 69-70, 2021 Jan.
Article in En | MEDLINE | ID: mdl-33208621
ABSTRACT
A 74-year-old man with a history of prostate cancer with proven osseous metastatic disease underwent Ga-prostate-specific membrane antigen (PSMA) PET/CT under antiandrogen therapy. The scan revealed a long segment of increased PSMA tracer uptake within the right sciatic nerve, which appeared edematous and swollen, and the respective ganglia. Clinically, the patient suffered from pain and paresis in the right leg. As infiltration of a long segment of a single nerve seems unlikely, primarily neuronal disease such as neuritis (induced by metastases or radiotherapy) was considered. The observed uptake of PSMA-targeting PET tracers may then represent a peripheral nerve disorder.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peripheral Nerves / Edetic Acid / Positron Emission Tomography Computed Tomography / Ganglia Limits: Aged / Humans / Male Language: En Journal: Clin Nucl Med Year: 2021 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peripheral Nerves / Edetic Acid / Positron Emission Tomography Computed Tomography / Ganglia Limits: Aged / Humans / Male Language: En Journal: Clin Nucl Med Year: 2021 Document type: Article