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Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy.
Byrne, Noel J; Lee, Amy C; Kostas, James; Reid, John C; Partridge, Andrea T; So, Sung-Sau; Cowan, Joseph E; Abeywickrema, Pravien; Huang, Hua; Zebisch, Matthias; Barker, John J; Soisson, Stephen M; Brooun, Alexei; Su, Hua-Poo.
Affiliation
  • Byrne NJ; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA. Electronic address: noel_byrne3@merck.com.
  • Lee AC; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Kostas J; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Reid JC; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Partridge AT; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • So SS; Department of Computational and Structural Sciences, Merck & Co., Inc., Kenilworth, NJ, USA.
  • Cowan JE; Department of Discovery Sample Management, Merck & Co., Inc., Rahway, NJ, USA.
  • Abeywickrema P; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Huang H; Evotec, Ltd., Princeton, NJ, USA.
  • Zebisch M; Evotec, Ltd., Abingdon, Oxfordshire, UK.
  • Barker JJ; Evotec, Ltd., Abingdon, Oxfordshire, UK.
  • Soisson SM; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Brooun A; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Su HP; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
Protein Expr Purif ; 179: 105796, 2021 03.
Article in En | MEDLINE | ID: mdl-33221505
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Fusion Proteins / Membrane Glycoproteins / Receptors, Immunologic / Molecular Chaperones / Crystallization Limits: Humans Language: En Journal: Protein Expr Purif Journal subject: BIOLOGIA MOLECULAR Year: 2021 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Fusion Proteins / Membrane Glycoproteins / Receptors, Immunologic / Molecular Chaperones / Crystallization Limits: Humans Language: En Journal: Protein Expr Purif Journal subject: BIOLOGIA MOLECULAR Year: 2021 Document type: Article Country of publication: United States