Quantitative ultrasound delta-radiomics during radiotherapy for monitoring treatment responses in head and neck malignancies.
Future Sci OA
; 6(9): FSO624, 2020 Sep 04.
Article
in En
| MEDLINE
| ID: mdl-33235811
ABSTRACT
AIM:
We investigated quantitative ultrasound (QUS) in patients with node-positive head and neck malignancies for monitoring responses to radical radiotherapy (RT). MATERIALS &METHODS:
QUS spectral and texture parameters were acquired from metastatic lymph nodes 24 h, 1 and 4 weeks after starting RT. K-nearest neighbor and naive-Bayes machine-learning classifiers were used to build prediction models for each time point. Response was detected after 3 months of RT, and patients were classified into complete and partial responders.RESULTS:
Single-feature naive-Bayes classification performed best with a prediction accuracy of 80, 86 and 85% at 24 h, week 1 and 4, respectively.CONCLUSION:
QUS-radiomics can predict RT response at 3 months as early as 24 h with reasonable accuracy, which further improves into 1 week of treatment.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Prognostic_studies
Language:
En
Journal:
Future Sci OA
Year:
2020
Document type:
Article
Affiliation country:
Canada