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WNT: an unexpected tumor suppressor in medulloblastoma.
Manoranjan, Branavan; Adile, Ashley A; Venugopal, Chitra; Singh, Sheila K.
Affiliation
  • Manoranjan B; Section of Neurosurgery, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
  • Adile AA; Departments of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Venugopal C; Surgery, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Singh SK; Departments of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
Mol Cell Oncol ; 7(6): 1834903, 2020.
Article in En | MEDLINE | ID: mdl-33241114
ABSTRACT
Medulloblastoma (MB) represents the most common malignant pediatric brain tumor and is defined by four molecular subgroups with WNT MB having the most favorable prognosis. Our work provides a rational therapeutic option in which the protective effects of WNT-driven MBs may be augmented in Group 3 and 4 MB.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Mol Cell Oncol Year: 2020 Document type: Article Affiliation country: Canada Publication country: EEUU / ESTADOS UNIDOS / ESTADOS UNIDOS DA AMERICA / EUA / UNITED STATES / UNITED STATES OF AMERICA / US / USA
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Mol Cell Oncol Year: 2020 Document type: Article Affiliation country: Canada Publication country: EEUU / ESTADOS UNIDOS / ESTADOS UNIDOS DA AMERICA / EUA / UNITED STATES / UNITED STATES OF AMERICA / US / USA