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The alkaloid, soyauxinium chloride, displays remarkable cytotoxic effects towards a panel of cancer cells, inducing apoptosis, ferroptosis and necroptosis.
Mbaveng, Armelle T; Noulala, Cédric G T; Samba, Anne R M; Tankeo, Simplice B; Abdelfatah, Sara; Fotso, Ghislain W; Happi, Emmanuel N; Ngadjui, Bonaventure T; Beng, Veronique P; Kuete, Victor; Efferth, Thomas.
Affiliation
  • Mbaveng AT; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon. Electronic address: armbatsa@yahoo.fr.
  • Noulala CGT; Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, P.O. Box 812, Yaoundé, Cameroon. Electronic address: cedric.noulala@hotmail.fr.
  • Samba ARM; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon; Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon. Electronic address: annecesarine@gmail.com.
  • Tankeo SB; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon. Electronic address: simplicetankeo@yahoo.fr.
  • Abdelfatah S; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany. Electronic address: saabdelf@uni-mainz.de.
  • Fotso GW; Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, P.O. Box 812, Yaoundé, Cameroon. Electronic address: ghis152001@gmail.com.
  • Happi EN; Department of Chemistry, Faculty of Science, University of Douala, Douala, Cameroon. Electronic address: ngeufa@yahoo.fr.
  • Ngadjui BT; Department of Organic Chemistry, Faculty of Science, University of Yaoundé 1, P.O. Box 812, Yaoundé, Cameroon. Electronic address: ngadjuibt@yahoo.fr.
  • Beng VP; Department of Biochemistry, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon. Electronic address: v.penlap@yahoo.fr.
  • Kuete V; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon. Electronic address: kuetevictor@yahoo.fr.
  • Efferth T; Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, University of Mainz, Staudinger Weg 5, 55128, Mainz, Germany. Electronic address: efferth@uni-mainz.de.
Chem Biol Interact ; 333: 109334, 2021 Jan 05.
Article in En | MEDLINE | ID: mdl-33245930
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Regulated Cell Death / Antineoplastic Agents Limits: Humans Language: En Journal: Chem Biol Interact Year: 2021 Document type: Article Country of publication: Ireland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Regulated Cell Death / Antineoplastic Agents Limits: Humans Language: En Journal: Chem Biol Interact Year: 2021 Document type: Article Country of publication: Ireland